Dutch Consortium for Healthcare Evaluation in Obstetrics and Gynaecology NVOG Consortium
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First round grant approvals ZonMw 2012

A list of the first round grant approvals for new studies in gynaecology, fertility and obstetrics:

-        APPel: RCT comparing levonorgestrel-releasing intrauterine device
with hysteroscopic polypectomy in the treatment of heavy
menstrual bleeding.

-    Cost-effectiveness of robot-assisted surgery

-         Immunoglobulin therapy during pregnancy to prevent congenital cytomegalovirus infection

-         The Dutch STRIDER (Sildenafil Therapy in Dismalprognosis Early-onset intrauterine growth restriction) trial

-         Quadruple P study (Pessary or Progesterone to PreventPreterm delivery in women with short cervical length)

-         APOSTEL III (Nifedipine versus Atosiban in thetreatment of threatened preterm labour)

-         STOP or GO? (Effect of SSRIs during pregnancy on infant and maternal health: a multicenterrandomized controlled trial)

-         SCALP trial (Effectiveness of fetal scalp blood sampling for the prevention
of cesarean section in case of suspected fetal distress during
labor (SCALP-trial); a randomized controlled multicenter study)

-         HYPITAT III (pre-existent HYPertension Interventiontrial At Term)

-         OPTIP (The optimal treatment for severe preeclampsia. Patient safety and improvement of maternal and neonatal outcome)

-         Is IVF really effective in women older than 38: amulti-centre randomized controlled trial comparing IVF to expectant managementpossibly leading to de-implementation

-         T4Life: Levothyroxine for euthyroid women withrecurrent miscarriage and positive TPO antibodies

-         Superovulation in Intra uterine insemination: rFSH orClomifene citrate?

-         MASTER: Cost-effectiveness of IUI, IVF and ICSI formale subfertility. The Male Subfertility Therapy effectiveness RCTs

-    Low-molecular-weight heparin to prevent recurrent VTE: what
is the right dose in pregnant women? (Highlow Study)

-    Anticoagulants to improve live birth in women with recurrent
miscarriage and thrombophilia: the ALIFE2 trial


Summaries of all study proposals (ppt)

Presentation "Quality circle in obstetrics and gynaecology" by Ben Willem Mol (pdf)